Amsterdam is not a a very wheelchair-friendly city. If fact, with all those cobbles, uneven pavements and bike lanes, it must be pretty impossible in the centre. I've just done a quick websurf on rolstoelgebruikers (wheelchair users) and all the hits seem to be telling me about the lack of wheelchair access. For example, if you want to visit Madame Tussauds you have to phone and let them know first - that's if you can manoeuvre your wheelchair over those bloody cobbles in the first place.